The Vampire war refers to the war between the Vampire Courts, mainly the Red Court, and the White Council of Wizards. If the Red Court defeats the White Council, the vampires will take control and do whatever they want. They will grab all of the places in the world that are already in chaos. They’ll spread from Central America to Africa, the Middle East, places that were the former USSR under Stalin and some parts of Asia—and then they’ll expand from there. The White Court will move on “civilized” places. Humans will be on their own with no protection from supernatural predators.
Harry Dresden, a wizard of the White Council, began the war when he killed Bianca St. Claire, a Red Court vampire, in Chicago.